Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708109 | 0.94 | AGTR1 (0.40) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9707900 | 0.92 | AGTR1 (0.43) | AGTR1AGTR2PPARGKMT2ATSHR | |
| SCHEMBL9708404 | 0.91 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9708139 | 0.91 | TSHR (0.42) | AGTR1AGTR2PPARGKMT2AALDH1A1 | |
| SCHEMBL9707542 | 0.90 | AGTR1 (0.43) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL9707548 | 0.90 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9707791 | 0.89 | AGTR1 (0.40) | AGTR1AGTR2PPARGKMT2AGAA | |
| SCHEMBL9708413 | 0.89 | AGTR1 (0.38) | AGTR1AGTR2KMT2AALDH1A1 | |
| SCHEMBL9708693 | 0.89 | AGTR1 (0.41) | AGTR1AGTR2PPARGKMT2AALDH1A1 | |
| SCHEMBL9708953 | 0.89 | AGTR1 (0.50) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |