⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700069 | 0.79 | — | — | |
| SCHEMBL3765030 | 0.77 | — | — | |
| SCHEMBL363772 | 0.77 | — | — | |
| SCHEMBL6385617 | 0.74 | TDP1 (0.33) | — | |
| SCHEMBL28252 | 0.74 | — | — | |
| SCHEMBL8834483 | 0.73 | — | — | |
| SCHEMBL2888616 | 0.73 | DAO (0.34) | — | |
| SCHEMBL2520189 | 0.73 | — | — | |
| SCHEMBL7465348 | 0.73 | — | — | |
| SCHEMBL7466739 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | claimed |
| CN-108350034-B | Antimicrobial polymyxin derived compounds | 莫纳什大学 | 2022-03-11 | — | — | CN | claimed |
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | MONASH UNIVERSITY (AU) | 2022-01-18 | — | — | US | claimed |
| EP-2785695-B1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-06-17 | — | — | EP | claimed |
| US-20180282374-A1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | MONASH UNIVERSITY (AU) | 2018-10-04 | — | — | US | claimed |
| EP-3356387-A1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | Monash University (AU) | 2018-08-08 | — | — | EP | claimed |
| US-9133158-B2 | Bicyclic dihydroisoquinoline-1-one derivatives | HOFFMAN-LA ROCHE INC. (US) | 2015-09-15 | — | — | US | claimed |
| EP-2785695-A1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2014-10-08 | — | — | EP | claimed |
| US-20130143863-A1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2013-06-06 | — | — | US | claimed |
| WO-2013079452-A1 | NEW BICYCLIC DIHYDROISOQUINOLINE-1-ONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-06-06 | — | — | WO | claimed |
| EP-0763530-B1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | BAYER AGROCHEM KK (JP) | 2001-12-05 | — | — | EP | claimed |
| US-5849767-A | Chloropyridylcarbonyl derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1998-12-15 | — | — | US | claimed |
| EP-0763530-A1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | NIHON BAYER AGROCHEM K.K. (JP) | 1997-03-19 | — | — | EP | claimed |
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023171783-A1 | PYRAZOLE COMPOUND, AND NOXIOUS ORGANISM CONTROL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2023-09-14 | — | — | WO | disclosed |
| CN-113512029-B | Preparation and application of substituted pyrazole compound containing pyrimidinamine | 沈阳中化农药化工研发有限公司 | 2023-01-24 | — | — | CN | disclosed |
| EP-0763530-A1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | NIHON BAYER AGROCHEM K.K. (JP) | 1997-03-19 | — | — | EP | disclosed |
| EP-0763530-A1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | NIHON BAYER AGROCHEM K.K. (JP) | 1997-03-19 | — | — | EP | disclosed |
| EP-0763530-A1 | Chloropyridylcarbonyl derivatives and their use as microbiocides | NIHON BAYER AGROCHEM K.K. (JP) | 1997-03-19 | — | — | EP | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |