Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914137 | 0.77 | PPM1B (0.43) | PPM1BPTPN1PPP1CCTSHRALDH1A1 | |
| SCHEMBL6983038 | 0.74 | L3MBTL1 (0.56) | TSHRALDH1A1KDM4ETP53MEN1 | |
| SCHEMBL9259639 | 0.73 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRALDH1A1 | |
| SCHEMBL24517229 | 0.70 | PPM1B (0.42) | PPM1BPTPN1PPP1CCTSHRALDH1A1 | |
| SCHEMBL29102252 | 0.69 | PPM1B (0.41) | PPM1BPTPN1PPP1CCTSHRALDH1A1 | |
| SCHEMBL11484005 | 0.68 | ATM (0.33) | PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL15525765 | 0.67 | PPM1B (0.36) | PPM1BPTPN1PPP1CCTSHRALDH1A1 | |
| Potassium SCHEMBL30343279 | 0.67 | KAT2A (0.31) | — | |
| SCHEMBL29004519 | 0.67 | KAT2A (0.31) | — | |
| SCHEMBL12966496 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220034-B1 | MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS | ICI AMERICAS INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| US-4701485-A | Malonate-based light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-10-20 | — | — | US | disclosed |
| EP-0220034-A2 | Malonate derivatives useful as light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-04-29 | — | — | EP | disclosed |