Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180341 | 0.80 | CTDSP1 (0.47) | CTDSP1GAAKMT2AL3MBTL1LMNA | |
| SCHEMBL10594774 | 0.77 | CTDSP1 (0.48) | CTDSP1GAAKMT2AL3MBTL1LMNA | |
| SCHEMBL9708919 | 0.76 | MAPK1 (0.39) | LMNAMAPK1 | |
| SCHEMBL1736191 | 0.74 | GAA (0.48) | CTDSP1GAAKMT2AL3MBTL1LMNA | |
| SCHEMBL18105045 | 0.72 | ATM (0.38) | GAAKMT2ALMNAMAPK1ALDH1A1 | |
| SCHEMBL13282718 | 0.71 | CTDSP1 (0.56) | CTDSP1GAAKMT2AL3MBTL1LMNA | |
| SCHEMBL6976939 | 0.71 | GAA (0.44) | CTDSP1GAAKMT2AL3MBTL1LMNA | |
| SCHEMBL5243257 | 0.71 | CTDSP1 (0.40) | CTDSP1GAAKMT2AL3MBTL1LMNA | |
| SCHEMBL7563295 | 0.70 | KMT2A (0.45) | CTDSP1GAAKMT2AL3MBTL1LMNA | |
| SCHEMBL28408748 | 0.70 | CTDSP1 (0.65) | CTDSP1GAAKMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220034-B1 | MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS | ICI AMERICAS INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| US-4701485-A | Malonate-based light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-10-20 | — | — | US | disclosed |
| EP-0220034-A2 | Malonate derivatives useful as light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-04-29 | — | — | EP | disclosed |