Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707819 | 0.93 | AGTR1 (0.40) | TSHRHSD17B10AGTR1AGTR2 | |
| SCHEMBL9708938 | 0.91 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9708940 | 0.90 | ADORA1 (0.43) | ADORA1TSHRHSD17B10AGTR1ALDH1A1 | |
| SCHEMBL9708059 | 0.87 | AGTR1 (0.40) | ADORA1AGTR1AGTR2 | |
| SCHEMBL9707434 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9707309 | 0.86 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9708550 | 0.85 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9707881 | 0.85 | AGTR1 (0.37) | TSHRAGTR1ALDH1A1AGTR2 | |
| SCHEMBL9708305 | 0.84 | ADORA1 (0.46) | ADORA1TSHRHSD17B10AGTR1ALDH1A1 | |
| SCHEMBL9708199 | 0.84 | AGTR1 (0.40) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |