Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.87 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.55 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.50 |
| ▸ | AKT1 | P31749 | 3/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440293 | 0.88 | PIK3CA (0.69) | PIK3CACAMKK1CAMKK2ACVR1MAP4K4 | |
| SCHEMBL19618305 | 0.87 | PIK3CA (0.68) | PIK3CACAMKK1CAMKK2ACVR1AURKB | |
| SCHEMBL19618388 | 0.87 | PIK3CA (0.68) | PIK3CACAMKK1CAMKK2ACVR1AURKB | |
| SCHEMBL17320781 | 0.87 | PIK3CA (0.86) | PIK3CACAMKK1CAMKK2ACVR1MAP4K4 | |
| SCHEMBL28084614 | 0.85 | PIK3CA (0.66) | PIK3CACAMKK1CAMKK2ACVR1MAP4K4 | |
| SCHEMBL730188 | 0.85 | PIK3CA (0.87) | PIK3CAACVR1MAP4K4AKT1ALK | |
| SCHEMBL12074333 | 0.85 | PIK3CA (0.65) | PIK3CACAMKK1CAMKK2ACVR1MAP4K4 | |
| SCHEMBL19618397 | 0.84 | PIK3CA (0.64) | PIK3CACAMKK1CAMKK2ACVR1 | |
| SCHEMBL17320796 | 0.84 | PIK3CA (0.64) | PIK3CACAMKK1CAMKK2ACVR1MAP4K4 | |
| SCHEMBL529894 | 0.84 | PIK3CA (0.64) | PIK3CACAMKK1CAMKK2ACVR1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992008604-A1 | FABRIC BASED ARTICLES HAVING IMPROVED PENETRATION RESISTANCE | ALLIED-SIGNAL INC. (US) | 1992-05-29 | — | — | WO | disclosed |