Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147633 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL6631569 | 0.79 | TSHR (0.48) | ALDH1A1SRD5A2L3MBTL1MAPTGAA | |
| SCHEMBL7472556 | 0.78 | NPC1 (0.58) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM | |
| SCHEMBL9066312 | 0.76 | ALDH1A1 (0.93) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM | |
| SCHEMBL314267 | 0.76 | ALDH1A1 (0.93) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM | |
| SCHEMBL49952 | 0.74 | ALDH1A1 (0.70) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM | |
| Benzophenone SCHEMBL1695422 | 0.73 | ALDH1A1 (0.88) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM | |
| Benzophenone SCHEMBL27436227 | 0.73 | ALDH1A1 (0.88) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM | |
| Benzophenone SCHEMBL6061130 | 0.73 | ALDH1A1 (1.00) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM | |
| Benzophenone SCHEMBL30537001 | 0.73 | ALDH1A1 (1.00) | ALDH1A1SRD5A2PBRM1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487423-A1 | Benzoselenazolinone derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-27 | — | — | EP | claimed |