Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761848 | 1.00 | TSHR (0.57) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL325190 | 0.98 | TSHR (0.54) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL8971295 | 0.93 | TSHR (0.50) | TSHRNAAAHPGDHCAR2LMNA | |
| SCHEMBL3105371 | 0.89 | TSHR (0.42) | TSHRNAAAHPGDHCAR2RAD52 | |
| SCHEMBL10764193 | 0.86 | TSHR (0.38) | TSHRHPGDHCAR2LMNAALDH1A1 | |
| SCHEMBL236897 | 0.83 | TSHR (0.59) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL29117607 | 0.83 | TSHR (0.59) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL375393 | 0.83 | TSHR (0.59) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL374916 | 0.83 | TSHR (0.59) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL11142775 | 0.83 | TSHR (0.59) | TSHRNAAAHCAR2RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171267-A | Surface-modified self-passivating intraocular lenses | THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1992-12-15 | — | — | US | disclosed |
| WO-1992016168-A1 | SURFACE-MODIFIED SELF-PASSIVATING INTRAOCULAR LENSES | THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1992-10-01 | — | — | WO | disclosed |
| US-4994352-A | Optical memory media | THE DOW CHEMICAL COMPANY (US) | 1991-02-19 | — | — | US | disclosed |