Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909255 | 0.91 | THRB (0.35) | TSHRALDH1A1 | |
| SCHEMBL9709320 | 0.89 | TSHR (0.57) | TSHRALDH1A1CYP3A4HTTHPGD | |
| SCHEMBL10761848 | 0.89 | TSHR (0.57) | TSHRALDH1A1CYP3A4HTTHPGD | |
| SCHEMBL325190 | 0.87 | TSHR (0.54) | TSHRALDH1A1CYP3A4HTTHPGD | |
| SCHEMBL8971295 | 0.85 | TSHR (0.50) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL32686846 | 0.84 | TSHR (0.50) | TSHRALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL10456655 | 0.82 | TSHR (0.47) | TSHRALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL3748655 | 0.82 | TSHR (0.47) | TSHRALDH1A1CYP3A4HTTPOLB | |
| SCHEMBL7758552 | 0.81 | TSHR (0.44) | TSHR | |
| SCHEMBL10764193 | 0.81 | TSHR (0.38) | TSHRALDH1A1POLBTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128294-A1 | Optical Material and Method for Modifying the Refractive Index | UNIV ROCHESTER (US) | 2021-05-06 | — | — | US | disclosed |
| US-10893936-B2 | Optical device and method for modifying the refractive index of an optical material | UNIVERSITY OF ROCHESTER (US) | 2021-01-19 | — | — | US | disclosed |
| US-10543076-B2 | Optical material and method for modifying the refractive index | UNIVERSITY OF ROCHESTER (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190240002-A1 | OPTICAL DEVICE AND METHOD FOR MODIFYING THE REFRACTIVE INDEX OF AN OPTICAL MATERIAL | UNIV ROCHESTER (US) | 2019-08-08 | — | — | US | disclosed |
| US-10299909-B2 | Optical device and method for modifying the refractive index of an optical material | UNIVERSITY OF ROCHESTER (US) | 2019-05-28 | — | — | US | disclosed |
| US-20170181846-A1 | Optical Material and Method for Modifying the Refractive Index | UNIV ROCHESTER (US) | 2017-06-29 | — | — | US | disclosed |
| US-9622912-B2 | Method for modifying the refractive index of an optical material | UNIVERSITY OF ROCHESTER (US) | 2017-04-18 | — | — | US | disclosed |
| US-20150126979-A1 | Method for Modifying the Refractive Index of an Optical Material | UNIVERSITY OF ROCHESTER | 2015-05-07 | — | — | US | disclosed |
| US-8932352-B2 | Optical material and method for modifying the refractive index | UNIVERSITY OF ROCHESTER (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130178934-A1 | Optical Material and Method for Modifying the Refractive Index | UNIVERSITY OF ROCHESTER | 2013-07-11 | — | — | US | disclosed |
| US-7789910-B2 | Optical material and method for modifying the refractive index | BAUSCH & LOMB INCORPORATED (US) | 2010-09-07 | — | — | US | disclosed |
| EP-2032102-B1 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX | BAUSCH & LOMB (US) | 2010-07-28 | — | — | EP | disclosed |
| US-20090143858-A1 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX | SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) | 2009-06-04 | — | — | US | disclosed |
| EP-2032102-A2 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX | Bausch & Lomb Incorporated (US) | 2009-03-11 | — | — | EP | disclosed |
| US-20080001320-A1 | Optical Material and Method for Modifying the Refractive Index | SOLTA MEDICAL IRELAND LIMITED (IE) | 2008-01-03 | — | — | US | disclosed |
| WO-2008002796-A2 | OPTICAL MATERIAL AND METHOD FOR MODIFYING THE REFRACTIVE INDEX | BAUSCH & LOMB INCORPORATED (US) | 2008-01-03 | — | — | WO | disclosed |
| US-6852820-B2 | Method for preparing acrylic copolymer materials suitable for ophthalmic devices | NIDEK CO., LTD. (JP) | 2005-02-08 | — | — | US | disclosed |
| US-20020151667-A1 | Method for preparing acrylic copolymer materials suitable for ophthalmic devices | NIDEK CO., LTD. | 2002-10-17 | — | — | US | disclosed |
| EP-1035142-A1 | Acrylic copolymer materials suitable for ophthalmic devices | Nidek Co., Ltd. (JP) | 2000-09-13 | — | — | EP | disclosed |
| US-5290892-A | Crosslinked phenylethyl acrylate-phenylethyl methacrylate | NESTLE S.A. (CH) | 1994-03-01 | — | — | US | disclosed |