SCHEMBL9709447

SCHEMBL9709447

Cc1ccc(S(=O)(=O)OCCCCC(N)=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
KMT2A Q03164 2/20 0.45
RAB9A P51151 1/20 0.45
STAT3 P40763 2/20 0.45
PSMD10 O75832 1/20 0.45
POLB P06746 1/20 0.42
F2 P00734 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
MAPT P10636 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2009235 0.95 ALDH1A1 (0.47) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL11217755 0.90 ALDH1A1 (0.45) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL19386611 0.89 ALDH1A1 (0.44) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL6238329 0.89 STAT3 (0.47) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL28974745 0.89 ALDH1A1 (0.44) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL890725 0.88 ALDH1A1 (0.50) ALDH1A1KMT2ASTAT3PSMD10CYP3A4
SCHEMBL25030574 0.88 STAT3 (0.46) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL9458218 0.88 STAT3 (0.46) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL17614843 0.88 STAT3 (0.46) ALDH1A1KMT2ARAB9ASTAT3PSMD10
SCHEMBL9872208 0.88 ALDH1A1 (0.43) ALDH1A1KMT2ARAB9ASTAT3PSMD10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992015557-A1 OMEGA-ALKANESULFONYLOXYALKANAMIDES EASTMAN KODAK COMPANY (US) 1992-09-17 WO disclosed