Tiopinac

Tiopinac

SCHEMBL9709495

CCC1Cc2cc(CC(=O)O)ccc2O1.O=C(O)Cc1ccc2c(c1)SCc1ccccc1C2=O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 4/20 0.69
MAPK14 Q16539 1/20 0.37
HRH1 P35367 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tiopinac SCHEMBL38905 0.83 AKR1B1 (1.00) AKR1B1MAPK14
Furofenac SCHEMBL35188 0.80 TBXA2R (0.46) AKR1B1HRH1
Furofenac SCHEMBL29413089 0.80 TBXA2R (0.46) AKR1B1HRH1
Tiopinac SCHEMBL11569336 0.79 AKR1B1 (0.86) AKR1B1MAPK14HRH1
SCHEMBL86394 0.77 AKR1B1 (0.81) AKR1B1MAPK14
Tiopinac SCHEMBL11570654 0.76 AKR1B1 (0.79) AKR1B1MAPK14
SCHEMBL38906 0.74 AKR1B1 (0.81) AKR1B1MAPK14HRH1
Tiopinac SCHEMBL11573830 0.73 AKR1B1 (0.79) AKR1B1MAPK14
Tiopinac SCHEMBL11825796 0.73 AKR1B1 (0.79) AKR1B1MAPK14
Tiopinac SCHEMBL11829030 0.73 AKR1B1 (0.79) AKR1B1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992021323-A1 USE OF LYSOPHOSPHATE ACIDS FOR THE TREATMENT OF SKIN WRINKLES THE PROCTER & GAMBLE COMPANY (US) 1992-12-10 WO disclosed