SCHEMBL9709548

SCHEMBL9709548

CCOP(=O)(OCC)C(CNCCO)OP(=O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.37
ANPEP P15144 2/20 0.33
GAA P10253 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
POLB P06746 1/20 0.31
PTPN1 P18031 1/20 0.31
ERAP2 Q6P179 1/20 0.30
SMPD1 P17405 3/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8604607 0.88 TSHR (0.36) PPARDANPEPGAACYP3A4CYP2C9
SCHEMBL19420896 0.67 TSHR (0.46) PPARDGAACYP3A4CYP2C9CYP2C19
Diethyl Hydrogen Phosphate SCHEMBL11442345 0.67 PPARD (0.45) PPARDCYP2C19CA12CA1CA2
SCHEMBL1394238 0.67 PPARD (0.42) PPARDGAACYP3A4CYP2C9CYP2C19
SCHEMBL15532056 0.65 PPARD (0.65) PPARDGAACYP2C9CYP2C19CA12
SCHEMBL7938332 0.65 PPARD (0.54) PPARDGAACYP2C9CYP2C19CA12
Diethanolamine SCHEMBL10629931 0.64 PPARD (0.40) PPARDANPEPCA12CA1CA2
SCHEMBL3427526 0.64 ANPEP (0.37) ANPEPPTPN1ERAP2SMPD1
Ethylene Glycol SCHEMBL16446354 0.62 PPARD (0.58) PPARD
SCHEMBL13575578 0.62 PPARD (0.48) PPARDGAACYP2C9CYP2C19CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992022559-A1 DIALKYL (DIALKOXYPHOSPHINYL)METHYL PHOSPHATES AS ANTI-INFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1992-12-23 WO disclosed