Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 5/20 | 0.58 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338244 | 0.89 | PDE7A (0.65) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1713219 | 0.89 | PDE7A (0.65) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL6930370 | 0.87 | PDE7A (0.59) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7643345 | 0.85 | GPR35 (0.47) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| Acetic Acid SCHEMBL8213274 | 0.81 | MAPT (0.67) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL3192750 | 0.80 | GPR35 (0.57) | PDE7AMAPTSMN1; SMN2MEN1KMT2A | |
| Diphenylsulfane SCHEMBL27370215 | 0.79 | PDE7A (0.56) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL19045039 | 0.79 | TDP1 (0.59) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11667729 | 0.78 | PDE7A (0.51) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2421409 | 0.78 | PDE7A (0.49) | PDE7APDE7BMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105560256-A | Pharmaceutical composition comprising aminobenzenesulfone derivatives for treating diseases associated with demyelination of neurons | SAMSUNG ELECTRONICS CO LTD | 2016-05-11 | — | — | CN | disclosed |
| WO-1992015919-A1 | LIQUID CRYSTAL ALIGNING AGENT AND ALIGNING AGENT-APPLIED LIQUID CRYSTAL DISPLAY DEVICE | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-09-17 | — | — | WO | disclosed |