Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092181 | 0.85 | TSHR (0.46) | TSHRALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL21738508 | 0.85 | TSHR (0.46) | TSHRALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL463195 | 0.84 | TSHR (0.70) | TSHRALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL12537385 | 0.81 | SMN1; SMN2 (0.47) | TSHRALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL153651 | 0.80 | TSHR (0.77) | TSHRALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL1639757 | 0.80 | TSHR (0.50) | TSHRGAATDP1EPHX2HDAC3 | |
| SCHEMBL29165358 | 0.80 | TSHR (0.61) | TSHRALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL11131919 | 0.79 | TSHR (0.65) | TSHRALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL637189 | 0.79 | ALDH1A1 (0.53) | TSHRALDH1A1SMN1; SMN2EPHX2LMNA | |
| SCHEMBL28252870 | 0.79 | TSHR (0.65) | TSHRALDH1A1GAASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |