Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709734 | 0.88 | TBXAS1 (0.48) | TBXAS1TBXA2R | |
| SCHEMBL9732860 | 0.82 | TBXAS1 (0.53) | TBXAS1F2TBXA2RCHRNB2CHRNA4 | |
| SCHEMBL9734351 | 0.81 | TBXAS1 (0.64) | TBXAS1TBXA2R | |
| SCHEMBL9709758 | 0.81 | TBXAS1 (0.64) | TBXAS1TBXA2R | |
| SCHEMBL9709586 | 0.77 | TBXAS1 (0.62) | TBXAS1TBXA2R | |
| SCHEMBL9709681 | 0.72 | TBXAS1 (0.77) | TBXAS1TBXA2R | |
| SCHEMBL9709648 | 0.71 | TBXAS1 (0.46) | TBXAS1TBXA2R | |
| SCHEMBL9709688 | 0.70 | TBXAS1 (0.61) | TBXAS1TBXA2R | |
| SCHEMBL9709988 | 0.70 | TBXAS1 (0.61) | TBXAS1TBXA2R | |
| SCHEMBL9709717 | 0.70 | TBXAS1 (0.84) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |