Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.51 |
| ▸ | ACP1 | P24666 | 3/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709673 | 0.95 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9709757 | 0.92 | AGTR1 (0.52) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9709925 | 0.89 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9709947 | 0.86 | AGTR1 (0.40) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9709682 | 0.86 | ACP1 (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL3058746 | 0.85 | AGTR1 (0.50) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9709839 | 0.85 | ACP1 (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9710183 | 0.85 | ACP1 (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9710180 | 0.85 | ACP1 (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9709764 | 0.85 | ACP1 (0.40) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |