Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709956 | 1.00 | HCAR2 (0.48) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL9709946 | 1.00 | HCAR2 (0.48) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL9709967 | 0.86 | HCAR2 (0.52) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL9709963 | 0.86 | HCAR2 (0.52) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL9709969 | 0.86 | HCAR2 (0.52) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL11277206 | 0.79 | — | — | |
| SCHEMBL11539420 | 0.73 | HCAR2 (0.55) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL8303646 | 0.73 | HCAR2 (0.55) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL8303644 | 0.73 | HCAR2 (0.55) | HCAR2MAPTKMT2ALMNANPSR1 | |
| SCHEMBL9315358 | 0.72 | MAPT (0.57) | HCAR2MAPTKMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020689-A1 | ANTIBACTERIAL PENEM DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 1992-11-26 | — | — | WO | disclosed |