Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710038 | 1.00 | FOLH1 (0.48) | FOLH1MMP3MMP8MMP9MMP1 | |
| SCHEMBL9709704 | 0.84 | FOLH1 (0.46) | FOLH1MMP3MMP8MMP9MMP1 | |
| SCHEMBL9709699 | 0.84 | FOLH1 (0.46) | FOLH1MMP3MMP8MMP9MMP1 | |
| SCHEMBL9709585 | 0.83 | FOLH1 (0.45) | FOLH1MMP3MMP8MMP9MMP1 | |
| SCHEMBL9709579 | 0.83 | FOLH1 (0.45) | FOLH1MMP3MMP8MMP9MMP1 | |
| SCHEMBL1858925 | 0.80 | HDAC1 (0.58) | SMN1; SMN2CPA3 | |
| SCHEMBL27649756 | 0.80 | MMP3 (0.46) | FOLH1MMP3MMP8MMP9MMP1 | |
| SCHEMBL27649771 | 0.80 | MMP3 (0.46) | FOLH1MMP3MMP8MMP9MMP1 | |
| SCHEMBL8878661 | 0.79 | TSHR (0.47) | MMP3MMP8MMP9MMP1EPHX2 | |
| SCHEMBL712393 | 0.79 | MAPT (0.56) | FOLH1EPHX2HTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |