Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365933 | 0.87 | — | — | |
| Water SCHEMBL9578432 | 0.87 | MAPT (0.50) | MAPTTDP1SMN1; SMN2LIN28AMEN1 | |
| Hydrochloric Acid SCHEMBL28196424 | 0.85 | MAPT (0.48) | MAPTTDP1SMN1; SMN2LIN28AMEN1 | |
| Piconol SCHEMBL537502 | 0.79 | TDP1 (0.48) | MAPTTDP1SMN1; SMN2LIN28AHRH3 | |
| 1-Methylimidazole SCHEMBL4869490 | 0.78 | HSD17B10 (0.46) | MAPTMEN1KMT2AHRH3HRH1 | |
| SCHEMBL29877048 | 0.76 | TDP1 (0.70) | MAPTTDP1SMN1; SMN2LIN28AKMT2A | |
| SCHEMBL804309 | 0.76 | TDP1 (0.70) | MAPTTDP1SMN1; SMN2LIN28AKMT2A | |
| SCHEMBL8604224 | 0.76 | TDP1 (0.70) | MAPTTDP1SMN1; SMN2LIN28AKMT2A | |
| SCHEMBL5482125 | 0.74 | SMN1; SMN2 (0.48) | MAPTTDP1SMN1; SMN2LIN28AMEN1 | |
| SCHEMBL12338697 | 0.73 | TDP1 (0.78) | MAPTTDP1SMN1; SMN2LIN28AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188400-B1 | OLIGOPEPTIDES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1992-07-08 | — | — | EP | disclosed |
| EP-0146785-B1 | PROCESS FOR THE PREPARATION OF PROTEASE INHIBITORS | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| EP-0188400-A2 | Oligopeptides, intermediates and process for their preparation | CIBA-GEIGY AG (CH) | 1986-07-23 | — | — | EP | disclosed |
| EP-0146785-A1 | Process for the preparation of protease inhibitors | CIBA-GEIGY AG (CH) | 1985-07-03 | — | — | EP | disclosed |