SCHEMBL804309

SCHEMBL804309

CCN(Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.70
MAPT P10636 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
LIN28A Q9H9Z2 1/20 0.70
KCNA5 P22460 2/20 0.49
KMT2A Q03164 1/20 0.47
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
TSHR P16473 1/20 0.46
DRD2 P14416 1/20 0.46
HTR2A P28223 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.46
HRH1 P35367 1/20 0.45
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29877048 0.96 TDP1 (0.70) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL8604224 0.96 TDP1 (0.70) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL12338697 0.92 TDP1 (0.78) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL6864949 0.90 TDP1 (0.81) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL138261 0.87 SMN1; SMN2 (0.83) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL11471516 0.86 TDP1 (0.62) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL16215876 0.86 TDP1 (0.58) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL13555816 0.86 TDP1 (0.62) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL15483659 0.85 TDP1 (0.53) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL13555815 0.85 MAPT (0.53) TDP1MAPTSMN1; SMN2LIN28AKCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302409-A1 DETERMINING PANCREAS DISEASE USING FUNCTIONAL IMAGING HEPATIQ, INC. (US) 2025-10-02 US disclosed
EP-3426740-B1 METHOD OF PREPARING AN OXIDATIVELY CURABLE COATING FORMULATION MILLIKEN INDUSTRIALS LTD (GB) 2024-09-11 EP disclosed
WO-2023279211-A1 METAL-CONTAINING POLYMERS FOR MASS CYTOMETRY THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2023-01-12 WO disclosed
US-11512222-B2 Method of preparing an oxidatively curable coating formulation BORCHERS GMBH (DE) 2022-11-29 US disclosed
CN-114525071-A Method for producing coating formulations curable by oxidation 美利肯工业有限公司 2022-05-24 CN disclosed
EP-3978488-A1 ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION Universitetet I Oslo (NO) 2022-04-06 EP disclosed
EP-3497095-B1 ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION UNIV OSLO (NO) 2021-07-14 EP disclosed
US-10981866-B2 Chemical conjugates of Evans Blue derivatives and their use as radiotherapy and imaging agents THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2021-04-20 US disclosed
US-20200384115-A1 TARGETED DELIVERY TO BETA CELLS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-12-10 US disclosed
US-20200231543-A1 CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2020-07-23 US disclosed
US-8211401-B2 Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof for inhibiting PSMA MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2012-07-03 US disclosed
US-20120070378-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD THE UNIVERSITY OF AKRON (US) 2012-03-22 US disclosed
US-20120070378-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD THE UNIVERSITY OF AKRON (US) 2012-03-22 US disclosed
US-20110243857-A1 SMART CONTRAST AGENTS FOR MRI IMAGING UNIVERSITE DE ROUEN (FR) 2011-10-06 US disclosed
US-20110243857-A1 SMART CONTRAST AGENTS FOR MRI IMAGING UNIVERSITE DE ROUEN (FR) 2011-10-06 US disclosed
US-20100298270-A1 Novel Compounds and Methods of Using Them SYNDAX PHARMACEUTICALS, INC. (US) 2010-11-25 US disclosed
US-20100178246-A1 TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF FOR INHIBITING PSMA MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2010-07-15 US disclosed
WO-2010075003-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD THE UNIVERSITY OF AKRON (US) 2010-07-01 WO disclosed
US-20100098633-A1 SELECTIVE SEPRASE INHIBITORS MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2010-04-22 US disclosed
US-20090175794-A1 INHIBITORS OF CARBONIC ANHYDRASE IX MOLECULAR INSIGHT PHARMACEUTICALS, INC. 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200384115-A1 TARGETED DELIVERY TO BETA CELLS IAPP, ZFR, ZC3H11A TDP1 2688/4885MAPT 1712/4885SMN1; SMN2 1727/4885
US-20100178246-A1 TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF FOR INHIBITING PSMA PSMA1, PSMA5, PSMA3 TDP1 3443/4885MAPT 811/4885SMN1; SMN2 3915/4885
US-20110243857-A1 SMART CONTRAST AGENTS FOR MRI IMAGING CALCOCO2, COIL, CDR2 TDP1 4503/4885MAPT 1148/4885SMN1; SMN2 524/4885
US-20100298270-A1 Novel Compounds and Methods of Using Them HDAC1, HDAC3, HDAC6 TDP1 1085/4885MAPT 2078/4885SMN1; SMN2 430/4885
US-10981866-B2 Chemical conjugates of Evans Blue derivatives and their use as radiotherapy and imaging agents RABL3, H1-4, SSTR3 TDP1 4069/4885MAPT 1099/4885SMN1; SMN2 501/4885
US-20100098633-A1 SELECTIVE SEPRASE INHIBITORS SLC6A7, DNPEP, PREP TDP1 3266/4885MAPT 1542/4885SMN1; SMN2 1942/4885
US-20090175794-A1 INHIBITORS OF CARBONIC ANHYDRASE IX CA9, CA12, CA1 TDP1 3377/4885MAPT 3380/4885SMN1; SMN2 3298/4885
US-20120070378-A1 LANTHANIDE ION COMPLEXES AND IMAGING METHOD INSR, KCNH3, CA9 TDP1 4543/4885MAPT 1478/4885SMN1; SMN2 4387/4885
US-20200231543-A1 CHEMICAL CONJUGATES OF EVANS BLUE DERIVATIVES AND THEIR USE AS RADIOTHERAPY AND IMAGING AGENTS RABL3, H1-4, SSTR3 TDP1 4069/4885MAPT 1099/4885SMN1; SMN2 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.