Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379210 | 0.86 | KDM4E (0.49) | KDM4ENPC1RAB9APARP1PARP10 | |
| SCHEMBL11175864 | 0.84 | ALDH1A1 (0.62) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL826392 | 0.84 | SMN1; SMN2 (0.53) | KDM4ENPC1RAB9ACA1CA2 | |
| SCHEMBL6225082 | 0.82 | NPC1 (0.49) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL2835948 | 0.81 | PARP1 (0.55) | KDM4ENPC1RAB9APARP1PARP10 | |
| SCHEMBL1807116 | 0.79 | PARP1 (0.53) | KDM4ENPC1RAB9APARP1PARP10 | |
| SCHEMBL12264144 | 0.78 | SMN1; SMN2 (0.51) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL3343162 | 0.78 | PARP1 (0.52) | KDM4ENPC1RAB9APARP1PARP10 | |
| SCHEMBL1034025 | 0.78 | ALDH1A1 (0.68) | NPC1RAB9APARP10CA1CA2 | |
| SCHEMBL1447373 | 0.78 | NPC1 (0.72) | KDM4ENPC1RAB9APARP1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021668-A1 | BENZOTHIAZEPINONES AND THEIR USE AS ANTICONVULSANTS | THE BOOTS COMPANY PLC (GB) | 1992-12-10 | — | — | WO | disclosed |