Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27380379 | 0.75 | ALDH1A1 (0.75) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| SCHEMBL2935620 | 0.74 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| SCHEMBL25187033 | 0.73 | MAPK1 (0.74) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| Biphenyl SCHEMBL27846163 | 0.73 | ALDH1A1 (0.71) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| SCHEMBL167524 | 0.73 | MAPK1 (0.74) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| SCHEMBL5096848 | 0.73 | ALDH1A1 (0.47) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| SCHEMBL28375748 | 0.71 | MAPK1 (0.71) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| Water SCHEMBL4868802 | 0.71 | MAPK1 (0.71) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| Ammonia Solution, Strong SCHEMBL9570816 | 0.71 | MAPK1 (0.71) | ALDH1A1LMNAPOLBMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL27456794 | 0.71 | MAPK1 (0.71) | ALDH1A1LMNAPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | claimed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | claimed |
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-108424377-B | Method for synthesizing asymmetric azoxybenzene compound | 温州大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | disclosed |
| WO-1992021666-A1 | ANGIOTENSIN II RECEPTOR ANTAGONIST THIAZOLE DEVIVATIVES | LABORATOIRES UPSA (FR) | 1992-12-10 | — | — | WO | disclosed |
| US-4110460-A | ANTIINFLAMMATORY, ANALGESIC | METABIO (FR) | 1978-08-29 | — | — | US | disclosed |