Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710129 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL9162635 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL8751877 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL9850712 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL8751831 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL9710151 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL8751956 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL8751862 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL8751865 | 1.00 | THRA (0.48) | THRATHRBS1PR3S1PR1S1PR2 | |
| SCHEMBL29200029 | 0.89 | MAPT (0.40) | THRATHRBS1PR3S1PR1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518636-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |