Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.59 |
| ▸ | PLAU | P00749 | 4/20 | 0.59 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710665 | 0.91 | F10 (0.56) | F10PLAUF2PRSS1PRSS2 | |
| SCHEMBL9710628 | 0.82 | F10 (0.53) | F10PLAUF2PRSS1PRSS2 | |
| SCHEMBL9710459 | 0.77 | F2 (0.47) | F10PLAUF2PRSS1PRSS2 | |
| Iodide SCHEMBL9710508 | 0.76 | F10 (0.51) | F10PLAUF2PRSS1PRSS2 | |
| Bicarbonate SCHEMBL9665131 | 0.76 | F10 (0.57) | F10PLAUF2PRSS1PLG | |
| SCHEMBL8954706 | 0.71 | F10 (0.52) | F10PLAUF2PLGHPN | |
| SCHEMBL8955009 | 0.71 | HTT (0.52) | F10PLAUF2PRSS1PLG | |
| SCHEMBL8954856 | 0.69 | F10 (0.50) | F10PLAUF2PRSS1PLG | |
| SCHEMBL9710610 | 0.69 | F10 (0.57) | F10PLAUF2PRSS1PLG | |
| Hydrochloric Acid SCHEMBL8720171 | 0.69 | POLB (0.55) | F10PLAUF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |