Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.51 |
| ▸ | F2 | P00734 | 7/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8954922 | 0.90 | F10 (0.51) | F10PRSS1F2PLGPLAU | |
| SCHEMBL8954706 | 0.89 | F10 (0.52) | F10F2PLGPLAU | |
| SCHEMBL8954875 | 0.84 | F10 (0.44) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL9710628 | 0.83 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL9710665 | 0.82 | F10 (0.56) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL8954993 | 0.81 | CASR (0.41) | F10PRSS1F2 | |
| SCHEMBL8954767 | 0.79 | F10 (0.50) | F10F2PLGPLAU | |
| Iodide SCHEMBL8954868 | 0.78 | F10 (0.51) | F10F2PLGPLAU | |
| Hydrochloric Acid SCHEMBL8954995 | 0.78 | F10 (0.49) | F10F2PLGPLAU | |
| SCHEMBL9710459 | 0.78 | F2 (0.47) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |