Threonine

Threonine

SCHEMBL971053

C[C@@H](O)[C@H](N)C(=O)O.N[C@@H](CS)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.67
SLC7A11 Q9UPY5 1/20 0.67
SLC7A5 Q01650 2/20 0.45
ENPEP Q07075 4/20 0.44
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
SLC1A1 P43005 3/20 0.41
ALDH1A1 P00352 1/20 0.36
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
GRIK1 P39086 2/20 0.36
GRIA2 P42262 2/20 0.36
GRIA4 P48058 2/20 0.36
GRIK3 Q13003 2/20 0.36
GRIK5 Q16478 2/20 0.36
GRIA1 P42261 1/20 0.36
GRIK2 Q13002 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL971052 1.00 PTGS1 (0.67) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL4493265 1.00 PTGS1 (0.67) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL27769582 1.00 PTGS1 (0.67) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL6391173 0.93 PTGS1 (0.57) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL6391172 0.93 PTGS1 (0.57) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL23883208 0.93 PTGS1 (0.57) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Leucine SCHEMBL3495955 0.91 SLC7A5 (0.62) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Isoleucine SCHEMBL3374935 0.89 PTGS1 (0.53) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Cystine SCHEMBL9051990 0.89 PTGS1 (0.53) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL17559245 0.89 PTGS1 (0.53) PTGS1SLC7A11SLC7A5ENPEPSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110020242-A1 HIGH-DENSITY LIPOPROTEIN-LIKE PEPTIDE-PHOSPHOLIPID SCAFFOLD (\"HPPS\") NANOPARTICLES UNIVERSITY HEALTH NETWORK (CA) 2011-01-27 US claimed
EP-2229411-A1 HIGH-DENSITY LIPOPROTEIN-LIKE PEPTIDE-PHOSPHOLIPID SCAFFOLD (\"HPPS\") NANOPARTICLES University Health Network (CA) 2010-09-22 EP claimed
WO-2009073984-A1 HIGH-DENSITY LIPOPROTEIN-LIKE PEPTIDE-PHOSPHOLIPID SCAFFOLD ('HPPS') NANOPARTICLES UNIVERSITY HEALTH NETWORK (CA) 2009-06-18 WO claimed
WO-2024076136-A1 FUSION PEPTIDE COMPLEX COMPRISING TRANSMEMBRANE DOMAIN AND USE THEREOF 주식회사 안단테에프엠 2024-04-11 WO disclosed
WO-2024049232-A1 ANTIBACTERIAL PEPTIDE CONSISTING OF TRANSMEMBRANE PEPTIDE DOMAIN AND BASIC OR POLAR AMINO ACIDS AT OPPOSITE ENDS THEREOF AND VARIANTS THEREOF 주식회사 안단테에프엠 2024-03-07 WO disclosed
EP-2362778-B1 COMPOSITIONS COMPRISING VITAMIN C TUTINO MARCO (IT) 2018-02-07 EP disclosed
EP-2362778-A2 COMPOSITIONS COMPRISING VITAMINS Tutino, Matteo (IT) 2011-09-07 EP disclosed
US-20110206792-A1 COMPOSITIONS COMPRISING VITAMINS TUTINO MATTEO 2011-08-25 US disclosed
CN-101052411-B VLP-antigen conjugates and their uses as vaccines CYTOS BIOTECHNOLOGY AG 2011-04-06 CN disclosed
EP-2271602-A2 SURFACTANT-BASED MONOLITHIC COLUMNS, METHODS FOR MAKING THE SAME, AND METHODS FOR USING THE SAME Georgia State University Research Foundation, Inc. (US) 2011-01-12 EP disclosed
US-7829321-B2 Method for the production of bacterial toxins BAXTER INTERNATIONAL INC. (US) 2010-11-09 US disclosed
US-20020165344-A1 Method for the production of bacterial toxins BAXTER HEALTHCARE S.A. (CH) 2002-11-07 US disclosed
EP-0831872-A4 POLYPEPTIDE COMPOUNDS THAT FORM BETA SHEETS TORREY PINES INST (US) 2002-10-28 EP disclosed
US-20020061555-A1 Method for the production of bacterial toxins BAXTER HEALTHCARE S.A. (CH) 2002-05-23 US disclosed
WO-2001074862-A2 METHOD FOR THE PRODUCTION OF BACTERIAL TOXINS BAXTER INTERNATIONAL INC. (US) 2001-10-11 WO disclosed
EP-0831872-A1 POLYPEPTIDE COMPOUNDS THAT FORM BETA SHEETS TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1998-04-01 EP disclosed
WO-1996037212-A1 POLYPEPTIDE COMPOUNDS THAT FORM β SHEETS TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1996-11-28 WO disclosed
WO-1994012205-A1 DYNORPHIN A SUPPRESSION OF NATURAL KILLER CELL ACTIVITY THE ROCKEFELLER UNIVERSITY (US) 1994-06-09 WO disclosed
EP-0056249-B1 SYNTHETIC ANTIGENIC COMPOSITION AND PROCESS FOR MAKING SAME New York Blood Center, Inc. (US) 1985-06-26 EP disclosed
EP-0056249-A2 Synthetic antigenic composition and process for making same New York Blood Center, Inc. (US) 1982-07-21 EP disclosed