Cystine

Cystine

SCHEMBL9051990

C[C@@H](O)[C@H](N)C(=O)O.NC(CSSC[C@H](N)C(=O)O)C(=O)O.N[C@@H](CS)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.53
SLC7A11 Q9UPY5 1/20 0.53
NOS2 P35228 3/20 0.37
NOS1 P29475 2/20 0.37
NOS3 P29474 1/20 0.37
SLC7A5 Q01650 2/20 0.37
ENPEP Q07075 3/20 0.37
KIF11 P52732 4/20 0.35
SLC1A3 P43003 2/20 0.34
SLC1A2 P43004 2/20 0.34
SLC1A1 P43005 1/20 0.34
ARG1 P05089 1/20 0.34
ARG2 P78540 1/20 0.34
BHMT Q93088 1/20 0.33
BHMT2 Q9H2M3 1/20 0.33
GLO1 Q04760 1/20 0.33
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cystine SCHEMBL15517596 0.91 SLC7A5 (0.43) PTGS1SLC7A11NOS2NOS1NOS3
Cystine SCHEMBL10776039 0.91 SLC7A5 (0.43) PTGS1SLC7A11NOS2NOS1NOS3
Cystine SCHEMBL10776054 0.91 SLC7A5 (0.43) PTGS1SLC7A11NOS2NOS1NOS3
Cystine SCHEMBL10776045 0.91 SLC7A5 (0.43) PTGS1SLC7A11NOS2NOS1NOS3
Threonine SCHEMBL27769582 0.89 PTGS1 (0.67) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL971053 0.89 PTGS1 (0.67) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL971052 0.89 PTGS1 (0.67) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Threonine SCHEMBL4493265 0.89 PTGS1 (0.67) PTGS1SLC7A11SLC7A5ENPEPSLC1A3
Cystine SCHEMBL457216 0.86 PTGS1 (0.73) PTGS1SLC7A11NOS2NOS1NOS3
Cystine SCHEMBL457219 0.86 PTGS1 (0.73) PTGS1SLC7A11NOS2NOS1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996004297-A9 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS 1996-05-02 WO claimed