⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309182 | 0.92 | — | — | |
| SCHEMBL9311308 | 0.91 | EDNRA (0.43) | — | |
| SCHEMBL8542927 | 0.90 | — | — | |
| SCHEMBL8549062 | 0.87 | — | — | |
| SCHEMBL9309527 | 0.87 | — | — | |
| SCHEMBL9310161 | 0.87 | — | — | |
| SCHEMBL9678139 | 0.86 | EDNRA (0.40) | — | |
| SCHEMBL9675510 | 0.85 | — | — | |
| SCHEMBL9678097 | 0.85 | AGTR2 (0.39) | — | |
| SCHEMBL9616278 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020674-A1 | 1H-IMIDAZOL-1-YL-METHYL BENZOFURAN DERIVATIVES, WITH THE IMIDAZOLYL MOIETY BEING SUBSTITUTED BY A CYCLOALKYL GROUP | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | claimed |