Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RORA | P35398 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710712 | 0.89 | PTGDR2 (0.39) | GAAALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL9711023 | 0.88 | CYP2D6 (0.33) | NR5A1KDM4ERORANPC1NR3C1 | |
| SCHEMBL9854932 | 0.82 | F9 (0.43) | F9PLAUNR5A1KDM4ERORA | |
| SCHEMBL9711028 | 0.79 | F9 (0.42) | F9PLAUGAASMN1; SMN2IMPDH2 | |
| SCHEMBL9710663 | 0.77 | AR (0.37) | GAASMN1; SMN2MAPTNPSR1IMPDH2 | |
| SCHEMBL9710630 | 0.72 | AR (0.50) | F9PLAUNR3C1ALDH1A1MAPT | |
| SCHEMBL9811757 | 0.71 | F9 (0.41) | F9PLAUNR5A1KDM4ERORA | |
| SCHEMBL8796518 | 0.71 | SMN1; SMN2 (0.52) | F9PLAUKDM4ENPC1GAA | |
| SCHEMBL9313708 | 0.71 | F9 (0.43) | F9PLAUNPSR1 | |
| SCHEMBL9315737 | 0.71 | KMT2A (0.39) | GAAALDH1A1LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018467-A1 | CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |