Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RORA | P35398 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315737 | 0.89 | KMT2A (0.39) | ALDH1A1GAALMNATP53SMN1; SMN2 | |
| SCHEMBL9854839 | 0.88 | LMNA (0.33) | F9PLAUNR5A1KDM4ERORA | |
| SCHEMBL9811757 | 0.85 | F9 (0.41) | F9PLAUNR5A1KDM4ERORA | |
| SCHEMBL9710756 | 0.82 | F9 (0.41) | F9PLAUNR5A1KDM4ERORA | |
| SCHEMBL9854882 | 0.78 | F9 (0.43) | F9PLAUNPSR1 | |
| SCHEMBL9313708 | 0.78 | F9 (0.43) | F9PLAUNPSR1 | |
| SCHEMBL9313692 | 0.77 | HSD17B1 (0.36) | KDM4EGAASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL9571177 | 0.76 | HPGD (0.46) | F9PLAUALDH1A1LMNAMAPT | |
| SCHEMBL9854821 | 0.75 | F9 (0.40) | F9PLAULMNASMN1; SMN2 | |
| SCHEMBL9811785 | 0.74 | P2RX7 (0.34) | F9PLAUNR5A1KDM4ERORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453842-A2 | Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |