Tetragastrin

Tetragastrin

SCHEMBL9710792

CSCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 10/20 0.70
CCKAR P32238 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetragastrin SCHEMBL31332160 1.00 CCKBR (0.70) CCKBRCCKAR
Tetragastrin SCHEMBL30999517 1.00 CCKBR (0.70) CCKBRCCKAR
Tetragastrin SCHEMBL30999542 1.00 CCKBR (0.70) CCKBRCCKAR
Tetragastrin SCHEMBL30999571 1.00 CCKBR (0.70) CCKBRCCKAR
Tetragastrin SCHEMBL9710788 1.00 CCKBR (0.70) CCKBRCCKAR
Tetragastrin SCHEMBL30999635 1.00 CCKBR (0.70) CCKBRCCKAR
SCHEMBL18054010 1.00 CCKBR (0.70) CCKBRCCKAR
Tetragastrin SCHEMBL30999572 1.00 CCKBR (0.70) CCKBRCCKAR
Tetragastrin SCHEMBL11568902 0.99 CCKBR (0.70) CCKBRCCKAR
SCHEMBL30999567 0.95 CCKBR (0.66) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090492-A1 TUMOR-ACTIVATED CELL ENGAGERS AND METHODS OF USE THEREOF Xilio Development, Inc. (US) 2026-04-30 WO claimed
EP-4644563-A1 IN SITU SEQUENCING LIBRARY CONSTRUCTION METHOD, IN SITU SEQUENCING METHOD, AND USE BGI Shenzhen (CN) 2025-11-05 EP claimed
US-20240238378-A1 METHODS AND CCK-B RECEPTOR AGONISTS FOR TREATING TINNITUS CITY UNIVERSITY OF HONG KONG (HK) 2024-07-18 US claimed
CN-118304408-A Methods and CCK-B receptor agonists for treating tinnitus 香港城市大学 2024-07-09 CN claimed
WO-2024138347-A1 IN SITU SEQUENCING LIBRARY CONSTRUCTION METHOD, IN SITU SEQUENCING METHOD, AND USE 深圳华大生命科学研究院 2024-07-04 WO claimed
WO-2023174433-A1 SOLID, SEMISOLID, OR LIQUID COMPOSITIONS FOR AUGMENTING THE STABILITY, PERMEABILITY AND BIOAVAILABILITY OF ACTIVE PHARMACEUTICAL SUBSTANCES Smart Pharmaceutical (Suzhou) Co., Ltd. (CN) 2023-09-21 WO claimed
WO-2023135398-A1 ANTIBODY-DRUG CONJUGATES FOR THERAPEUTIC USE MC SAF (FR) 2023-07-20 WO claimed
US-11278627-B2 Antibody-drug conjugates and the use of same in therapy MC SAF (FR) 2022-03-22 US claimed
WO-1992019253-A1 CCK ANALOGS CONTAINING α-SUBSTITUTED AMINO ACIDS WARNER-LAMBERT COMPANY (US) 1992-11-12 WO claimed
US-4794103-A Pharmaceutical compositions containing peptides of the cholecystokinin-cerulein group for the therapy of shock conditions and of respiratory and cardiocirculatory insufficiencies BERTOLINI ALFIO (IT) 1988-12-27 US claimed
WO-2026102462-A1 ENGINEERED CELLS FOR TREATING DIABETES CITY OF HOPE (US) 2026-05-15 WO disclosed
EP-4735047-A1 PEGYLATED LINKERS AND USES THEREOF Université de Tours (FR) 2026-05-06 EP disclosed
EP-4735046-A1 BIOCONJUGATION SYSTEMS AND USES THEREOF Université de Tours (FR) 2026-05-06 EP disclosed
US-12617815-B2 Barcoded XTEN polypeptides and compositions thereof, and methods for making and using the same AMUNIX PHARMACEUTICALS, INC. (US) 2026-05-05 US disclosed
WO-2026090492-A1 TUMOR-ACTIVATED CELL ENGAGERS AND METHODS OF USE THEREOF Xilio Development, Inc. (US) 2026-04-30 WO disclosed
EP-0405506-A1 Tetrapeptide type-B CCK receptor ligands ABBOTT LABORATORIES (US) 1991-01-02 EP disclosed
EP-0115227-B1 PEPTIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1987-03-18 EP disclosed
US-4530837-A Containing tryptophan COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1985-07-23 US disclosed
EP-0115227-A1 Peptide derivatives, process for their preparation and their pharmaceutical use COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1984-08-08 EP disclosed
US-4164571-A Medicament which antagonizes the action of gastrin and related polypeptides COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1979-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617815-B2 Barcoded XTEN polypeptides and compositions thereof, and methods for making and using the same SPPL2B, PTMS, ANPEP CCKBR 532/4885CCKAR 1274/4885
US-20240238378-A1 METHODS AND CCK-B RECEPTOR AGONISTS FOR TREATING TINNITUS CCKBR, CCKAR, NTSR2 CCKBR 1/4885CCKAR 2/4885
US-11278627-B2 Antibody-drug conjugates and the use of same in therapy CD47, TNFRSF9, VSIG8 CCKBR 4292/4885CCKAR 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.