Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079970 | 0.83 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL11079964 | 0.82 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL11808734 | 0.80 | MEN1 (0.42) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL10424599 | 0.77 | AKR1B1 (0.43) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL11636866 | 0.76 | KEAP1 (0.40) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL2779682 | 0.75 | PTPN2 (0.43) | KMT2AMAPK1MAPTLMNAAKR1B1 | |
| SCHEMBL2684375 | 0.75 | SLC6A4 (0.44) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL3532102 | 0.75 | KEAP1 (0.45) | KMT2AMAPK1MAPTAKR1B1KEAP1 | |
| SCHEMBL11420003 | 0.75 | AKR1B1 (0.42) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL1136796 | 0.75 | AKR1B1 (0.42) | KMT2AMEN1MAPK1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336769-B | Thienopyrimidine ketone acyl sulfonamide derivative as well as preparation method and application thereof | 山东大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113336769-A | Thienopyrimidone acylsulfonamide derivative and preparation method and application thereof | 山东大学 | 2021-09-03 | — | — | CN | claimed |
| CN-111249805-B | Electret nanofiber filtering material and preparation method thereof | 厦门理工学院 | 2022-07-12 | — | — | CN | disclosed |
| CN-111249805-A | Electret nanofiber filtering material and preparation method thereof | 厦门理工学院 | 2020-06-09 | — | — | CN | disclosed |
| CN-103980287-B | Containing the preparations and applicatio of the thienopyrimidines of chromone hydrazone structure | JIANGXI SCIENCE & TECHNOLOGY NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| US-9278958-B2 | Anti-cancer compounds | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D (BE) | 2016-03-08 | — | — | US | disclosed |
| CN-102485724-B | Substituted thiophene base pyrazolo-pyridines and medicinal use thereof | Institute of Toxicology and Drugs, Chinese Academy of Military Medical Sciences (CN) | 2015-08-12 | — | — | CN | disclosed |
| US-20150126559-A1 | NOVEL ANTI-CANCER COMPOUNDS | UNIVERSITA DEGLI STUDI DI FERRARA (IT) | 2015-05-07 | — | — | US | disclosed |
| CN-103980287-A | Preparation method and application of thienopyrimidine compound containing chromone hydrazone structure | UNIV JIANGXI NORMAL SCI & TECH | 2014-08-13 | — | — | CN | disclosed |
| CN-102471338-B | Novel azaheterocyclic compounds | MERCK PATENT GMBH | 2014-07-02 | — | — | CN | disclosed |
| CN-101437816-B | 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC | 2013-08-14 | — | — | CN | disclosed |
| CN-101437816-A | 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-101107253-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2008-01-16 | — | — | CN | disclosed |
| CN-101094845-A | Substituted thiophenes | AICURIS GMBH & CO KG (DE) | 2007-12-26 | — | — | CN | disclosed |
| CN-101061123-A | Thienopyridinone compounds and methods of treatment | EPIX DELAWARE INC (US) | 2007-10-24 | — | — | CN | disclosed |
| CN-1269793-A | Pyrimidin-2-oxo-4-one and pyrimidin-2-oxo-4-thione derivatives | NOVARTIS AG (CH) | 2000-10-11 | — | — | CN | disclosed |
| CN-1021051-C | THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING SAME | TANABE SEIYAKU CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| EP-0499376-A1 | Precipitation-induced asymmetric transformation of chiral alpha-amino acids and salts thereof | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| CN-1030584-A | Novel thiophene derivant and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-01-25 | — | — | CN | disclosed |
| US-4297489-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126559-A1 | NOVEL ANTI-CANCER COMPOUNDS | ATP5F1A, TP53, ABCF1 | KMT2A 2327/4885MEN1 1180/4885ALDH1A1 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.