Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160711 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL2169178 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL2167463 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL64593 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL20913726 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL29446779 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Ammonia Solution, Strong SCHEMBL5679172 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL26134181 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL1961059 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL2167884 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324692-B1 | PROCESS FOR THE PREPARATION OF HYDROXYALKYLATING AGENTS, THE AGENTS AS PREPARED AND THEIR USE | RHONE-POULENC SANTE (FR) | 1992-11-25 | — | — | EP | claimed |
| US-5023361-A | Process for preparing hydroxyalkylating agents, the agents so obtained, and their use | RHONE-POULENC SANTE (FR) | 1991-06-11 | — | — | US | claimed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | claimed |
| US-5023361-A | Process for preparing hydroxyalkylating agents, the agents so obtained, and their use | RHONE-POULENC SANTE (FR) | 1991-06-11 | — | — | US | disclosed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |