⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849774 | 0.85 | — | — | |
| SCHEMBL2591056 | 0.83 | LCK (0.63) | — | |
| SCHEMBL17545277 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL8419946 | 0.81 | LCK (0.67) | — | |
| SCHEMBL8417930 | 0.81 | LCK (0.67) | — | |
| SCHEMBL8419752 | 0.81 | LCK (0.67) | — | |
| SCHEMBL8417906 | 0.81 | LCK (0.67) | — | |
| SCHEMBL8417939 | 0.81 | LCK (0.67) | — | |
| SCHEMBL8418242 | 0.81 | LCK (0.67) | — | |
| SCHEMBL8418402 | 0.81 | LCK (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101544795-A | Polystyrene/two-dimensional silica compound and preparation method thereof | UNIV SHANGHAI | 2009-09-30 | — | — | CN | claimed |
| CN-114786724-A | Anti-aggregation agent, and pharmaceutical composition and medical device using same | 尼普洛株式会社 | 2022-07-22 | — | — | CN | disclosed |
| US-8217001-B2 | Modification of feeding behavior | IMPERIAL INNOVATIONS LIMITED | 2012-07-10 | — | — | US | disclosed |
| CN-101544795-B | Polystyrene/two-dimensional silica compound and preparation method thereof | UNIV SHANGHAI | 2012-03-28 | — | — | CN | disclosed |
| US-7868032-B2 | Prostamide receptor antagonists | ALLERGAN, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| CN-101544795-A | Polystyrene/two-dimensional silica compound and preparation method thereof | UNIV SHANGHAI | 2009-09-30 | — | — | CN | disclosed |
| US-20090209461-A1 | MODIFICATION OF FEEDING BEHAVIOR | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 2009-08-20 | — | — | US | disclosed |
| CN-101307143-A | Organic-inorganic composite lamellar compound with regular arrangement bromium and method for preparing same | UNIV SHANGHAI (CN) | 2008-11-19 | — | — | CN | disclosed |
| US-20080096240-A1 | NOVEL PROSTAMIDE RECEPTOR ANTAGONISTS | WOODWARD DAVID F | 2008-04-24 | — | — | US | disclosed |
| EP-1259522-A1 | LIGAND AND COMPLEX FOR CATALYTICALLY BLEACHING A SUBSTRATE | UNILEVER PLC (GB) | 2002-11-27 | — | — | EP | disclosed |
| WO-1997030045-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1997-08-21 | — | — | WO | disclosed |
| EP-0781801-A1 | Silica-filled rubber compositions containing dialkyleneamide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5641820-A | SULFUR VULCANIZABLE ELASTOMERS WITH COUPLING AGENTS, FOR TIRE TREADS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0776324-A1 | ENDOTHELIN ANTAGONISTS | Abbott Laboratories (US) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996006095-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-02-29 | — | — | WO | disclosed |
| US-5318984-A | Anticholesterol agents which inhibit acetyl coenzyme A transferase | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0372445-B1 | Imidazoles for the treatment of atherosclerosis | DU PONT MERCK PHARMA (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5166214-A | Enzyme inhibitors for anticholesterol agents, enzyme inhibitor and cardiovascular disorders | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| WO-1991018885-A1 | IMIDAZOLES FOR THE TREATMENT OF ATHEROSCLEROSIS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0372445-A1 | Imidazoles for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |