SCHEMBL971122

SCHEMBL971122

COc1ccccc1Br.[MgH2]

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.60
CA2 P00918 3/20 0.60
CA7 P43166 2/20 0.60
CA9 Q16790 2/20 0.60
CA12 O43570 1/20 0.60
CA4 P22748 1/20 0.60
CA14 Q9ULX7 1/20 0.60
L3MBTL1 Q9Y468 4/20 0.49
MAPT P10636 4/20 0.49
HPGD P15428 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 2/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CYP2C9 P11712 1/20 0.49
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
ADRA2B P18089 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29424769 0.97
SCHEMBL57602 0.97
Ammonia Solution, Strong SCHEMBL4275178 0.95 CA1 (0.60) CA1CA2CA7CA9CA12
Benzene SCHEMBL28837065 0.92 CA1 (0.57) CA1CA2CA7CA9CA12
Bromide SCHEMBL4665342 0.92 CA1 (0.57) CA1CA2CA7CA9CA12
Ethylene SCHEMBL28180370 0.92 CA1 (0.57) CA1CA2CA7CA9CA12
Cyanide SCHEMBL27876981 0.90 CA1 (0.55) CA1CA2CA7CA9CA12
Bicarbonate SCHEMBL28499138 0.86 HPGD (0.56) CA1CA2CA7CA9CA12
Acetone SCHEMBL27645095 0.86 LY96 (0.53) CA1CA2CA7CA9CA12
SCHEMBL11820506 0.84 L3MBTL1 (0.49) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184705-A Preparation method and application of diphosphine palladium complex 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-118184706-A Diphosphine palladium complex and application thereof 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-114044753-A Small molecular compound with anti-tumor metastasis function and preparation method thereof 广州市朝利良生物科技有限公司 2022-02-15 CN claimed
US-5623087-A Method for preparation of optically active diarylalanines NDSU-RESEARCH FOUNDATION (US) 1997-04-22 US claimed
WO-2024168037-A2 COMPOUNDS FOR TREATING OPIOID MISUSE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-15 WO disclosed
CN-118184705-A Preparation method and application of diphosphine palladium complex 中国石油天然气股份有限公司 2024-06-14 CN disclosed
CN-118184705-A Preparation method and application of diphosphine palladium complex 中国石油天然气股份有限公司 2024-06-14 CN disclosed
CN-118184997-A Binary polar polyketone and preparation method thereof 中国石油天然气股份有限公司 2024-06-14 CN disclosed
CN-118184996-A Ternary polar polyketone and preparation method thereof 中国石油天然气股份有限公司 2024-06-14 CN disclosed
CN-118184706-A Diphosphine palladium complex and application thereof 中国石油天然气股份有限公司 2024-06-14 CN disclosed
CN-117567511-A Complex, complex catalyst, and preparation method and application thereof 合肥中科科乐新材料有限责任公司 2024-02-20 CN disclosed
CN-117069717-A 2, 6-naphthyridine micromolecule derivative and preparation method thereof 江汉大学 2023-11-17 CN disclosed
EP-0024943-B1 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM TORAY INDUSTRIES, INC. (JP) 1983-08-17 EP disclosed
US-4356182-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-10-26 US disclosed
US-4316905-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-02-23 US disclosed
US-4301164-A FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS TORAY INDUSTRIES, INC. (JP) 1981-11-17 US disclosed
US-4291040-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1981-09-22 US disclosed
EP-0024943-A1 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them TORAY INDUSTRIES, INC. (JP) 1981-03-11 EP disclosed
US-4233296-A STEROIDS HAVING PROGESTOMIMETIC PROPERTIES ROUSSEL UCLAF (FR) 1980-11-11 US disclosed
US-4147695-A 11β-Substituted-Δ9 -steroids ROUSSEL UCLAF (FR) 1979-04-03 US disclosed