Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | SHBG | P04278 | 4/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711332 | 1.00 | CYP19A1 (0.37) | CYP19A1SHBGARCYP3A4SERPINA6 | |
| SCHEMBL9254164 | 1.00 | CYP19A1 (0.37) | CYP19A1SHBGARCYP3A4SERPINA6 | |
| SCHEMBL2602620 | 0.88 | HSD11B1 (0.31) | CYP3A4HSD11B1 | |
| SCHEMBL11043329 | 0.82 | GPBAR1 (0.59) | CYP19A1SHBGARCYP3A4SERPINA6 | |
| SCHEMBL11043325 | 0.82 | GPBAR1 (0.59) | CYP19A1SHBGARCYP3A4SERPINA6 | |
| SCHEMBL25420472 | 0.82 | PTPN1 (0.33) | CYP3A4HSD11B1 | |
| SCHEMBL5854103 | 0.73 | ESR1 (0.46) | CYP19A1SHBGARCYP3A4SERPINA6 | |
| SCHEMBL2602632 | 0.73 | ESR1 (0.46) | CYP19A1SHBGARCYP3A4SERPINA6 | |
| SCHEMBL2602644 | 0.71 | ESR2 (0.33) | CYP19A1CYP3A4ESR1ESR2 | |
| SCHEMBL2602645 | 0.71 | ESR1 (0.39) | CYP19A1SHBGARCYP3A4SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020684-A1 | HERBICIDAL OXATRICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |