Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711707 | 0.85 | HPD (0.48) | HPDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9711540 | 0.83 | HPD (0.49) | HPDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9711616 | 0.83 | HPD (0.46) | HPDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9711516 | 0.82 | HPD (0.48) | HPDALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9711711 | 0.82 | HPD (0.48) | HPDKDM4EALDH1A1MAPK1RAB9A | |
| SCHEMBL9711660 | 0.82 | HPD (0.51) | HPDALDH1A1MAPT | |
| SCHEMBL8467136 | 0.82 | HPD (0.46) | HPDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9711603 | 0.81 | KDM4E (0.43) | HPDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9711602 | 0.81 | HPD (0.46) | HPDMEN1KMT2AMAPK1MAPT | |
| SCHEMBL9711608 | 0.80 | KMT2A (0.47) | HPDKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |