⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3202722 | 0.97 | — | — | |
| Urea SCHEMBL11495730 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL8295 | 0.76 | — | — | |
| SCHEMBL6950834 | 0.76 | ALDH1A1 (0.56) | — | |
| SCHEMBL344664 | 0.76 | — | — | |
| SCHEMBL15144423 | 0.76 | — | — | |
| SCHEMBL10500046 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL10542559 | 0.74 | ALDH1A1 (0.79) | — | |
| SCHEMBL209024 | 0.73 | — | — | |
| SCHEMBL2592313 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530132-A | Preparation method of N-acyl amino acid surfactant | 盐城工学院 | 2024-08-23 | — | — | CN | claimed |
| CN-116768906-B | Tri-fused ring compound and preparation method and application thereof | 遵义医科大学珠海校区 | 2024-04-09 | — | — | CN | claimed |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | claimed |
| CN-115485259-A | Substituted hydroxystilbene compounds and derivatives, synthesis and use thereof | 凯楠公爵IP有限责任公司 | 2022-12-16 | — | — | CN | claimed |
| WO-2021127743-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2021-07-01 | — | — | WO | claimed |
| CN-107033157-B | Bisbenzylisoquinoline derivative and application thereof in preparing medicament for treating or preventing tumor | 贵州省中国科学院天然产物化学重点实验室 | 2020-05-05 | — | — | CN | claimed |
| US-10189812-B2 | Bi-benzyl isoquinoline derivative, preparation method and use thereof in hepatopathy treatment and prevention | THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUC (CN) | 2019-01-29 | — | — | US | claimed |
| CN-107207524-A | Bisbenzylisoquinolinderivative derivative, its preparation method and its purposes in the treatment and prevention of hepatopathy | 贵州省中国科学院天然产物化学重点实验室 | 2017-09-26 | — | — | CN | claimed |
| US-20170260161-A1 | BI-BENZYL ISOQUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF IN HEPATOPATHY TREATMENT AND PREVENTION | VERSITECH LIMITED (CN) | 2017-09-14 | — | — | US | claimed |
| CN-107033157-A | Bisbenzylisoquinolinderivative derivative and its purposes in preparing for treating or preventing the medicine of tumour | 贵州省中国科学院天然产物化学重点实验室 | 2017-08-11 | — | — | CN | claimed |
| WO-2005082347-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | APLLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-09-09 | — | — | WO | claimed |
| EP-1146788-A4 | AMIDE DERIVATIVES FOR ANTIANGIOGENIC AND/OR ANTITUMORIGENIC USE | UNIV VANDERBILT (US) | 2003-09-10 | — | — | EP | claimed |
| EP-1148783-A4 | CONVERTING COX INHIBITION COMPOUNDS THAT ARE NOT COX-2 SELECTIVE INHIBITORS TO DERIVATIVES THAT ARE COX-2 SELECTIVE INHIBITORS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | claimed |
| EP-1148783-A1 | CONVERTING COX INHIBITION COMPOUNDS THAT ARE NOT COX-2 SELECTIVE INHIBITORS TO DERIVATIVES THAT ARE COX-2 SELECTIVE INHIBITORS | Vanderbilt University (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1146788-A1 | AMIDE DERIVATIVES FOR ANTIANGIOGENIC AND/OR ANTITUMORIGENIC USE | Vanderbilt University (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000040087-A1 | CONVERTING COX INHIBITION COMPOUNDS THAT ARE NOT COX-2 SELECTIVE INHIBITORS TO DERIVATIVES THAT ARE COX-2 SELECTIVE INHIBITORS | VANDERBILT UNIVERSITY (US) | 2000-07-13 | — | — | WO | claimed |
| WO-2000040088-A1 | AMIDE DERIVATIVES FOR ANTIANGIOGENIC AND/OR ANTITUMORIGENIC USE | VANDERBILT UNIVERSITY (US) | 2000-07-13 | — | — | WO | claimed |
| EP-0001914-B1 | ANTIBACTERIALLY ACTIVE AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID AMIDES | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | claimed |
| US-4200635-A | MONIC ACID A AMIDES | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | claimed |
| EP-0001914-A2 | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides | BEECHAM GROUP PLC (GB) | 1979-05-16 | — | — | EP | claimed |