Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042794 | 0.81 | CCNE1 (0.41) | ALDH1A1L3MBTL1CCNE1CDK2GSK3B | |
| SCHEMBL27942905 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1L3MBTL1MAPK1CCNE1CDK2 | |
| SCHEMBL9717388 | 0.78 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2CDC25B | |
| SCHEMBL875061 | 0.77 | CCNE1 (0.40) | ALDH1A1MAPK1CCNE1CDK2GSK3B | |
| SCHEMBL10617309 | 0.77 | MEN1 (0.48) | ALDH1A1CCNE1CDK2GSK3BNPC1 | |
| SCHEMBL23191944 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPK1CCNE1CDK2 | |
| SCHEMBL15450611 | 0.77 | NOTUM (0.52) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL19730317 | 0.77 | MEN1 (0.46) | CCNE1CDK2GSK3BNPC1RAB9A | |
| SCHEMBL27904416 | 0.76 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2CDC25B | |
| SCHEMBL11563416 | 0.76 | MEN1 (0.50) | ALDH1A1CCNE1CDK2GSK3BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019274-A1 | TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION | MALLINCKRODT MEDICAL, INC. (US) | 1992-11-12 | — | — | WO | disclosed |