Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197584 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APGRHIF1A | |
| SCHEMBL15154503 | 0.83 | MEN1 (0.59) | ALDH1A1SRCLMNAMAPTMEN1 | |
| SCHEMBL9202310 | 0.82 | MEN1 (0.71) | ALDH1A1SRCLMNAMEN1KMT2A | |
| SCHEMBL24864976 | 0.81 | ALDH1A1 (0.72) | ALDH1A1SRCLMNAMAPTHSD17B10 | |
| SCHEMBL30804578 | 0.81 | ALDH1A1 (0.72) | ALDH1A1SRCLMNAMAPTHSD17B10 | |
| SCHEMBL9195565 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2ANLRP3 | |
| SCHEMBL9196968 | 0.81 | MEN1 (0.50) | ALDH1A1SRCLMNAMEN1KMT2A | |
| SCHEMBL7612454 | 0.80 | MEN1 (0.52) | ALDH1A1SRCMAPTMEN1KMT2A | |
| SCHEMBL9202386 | 0.80 | TP53 (0.51) | ALDH1A1HSD17B10MEN1KMT2APGR | |
| SCHEMBL9201791 | 0.79 | KMT2A (0.54) | ALDH1A1SRCLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |