SCHEMBL9712339

SCHEMBL9712339

COC(=O)C1C(O)=CC(=O)CC1C1(SC)CCC1

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
MAPK1 P28482 1/20 0.42
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15604500 0.72 ALDH1A1 (1.00) ALDH1A1MAPK1
SCHEMBL15944451 0.69 ALDH1A1 (0.47) ALDH1A1MAPK1
SCHEMBL9607196 0.69 ALDH1A1 (0.65) ALDH1A1MAPK1SRD5A2
SCHEMBL15945508 0.67 ALDH1A1 (0.44) ALDH1A1MAPK1
SCHEMBL15944453 0.67 ALDH1A1 (0.61) ALDH1A1MAPK1
SCHEMBL15994429 0.64 ALDH1A1 (0.60) ALDH1A1MAPK1
SCHEMBL13176291 0.63 ALDH1A1 (0.52) ALDH1A1MAPK1
SCHEMBL15944418 0.62 ALDH1A1 (0.50) ALDH1A1MAPK1
SCHEMBL15944380 0.62 ALDH1A1 (0.50) ALDH1A1MAPK1
SCHEMBL15944368 0.61 ALDH1A1 (0.49) ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5169988-A From unsaturated methyl ketone CIBA-GEIGY CORPORATION (US) 1992-12-08 US disclosed
US-5132462-A Sulfide, sulfonyl and sulfinyl compounds, agricultural use CIBA-GEIGY CORPORATION (US) 1992-07-21 US disclosed
US-5026899-A Acylcylohexanediones and the oxime ethers thereof with herbicidal and plant growth regulating properties CIBA-GEIGY CORPORATION (US) 1991-06-25 US disclosed
US-4909835-A Containing a sulfur substitution in position 5 CIBA-GEIGY CORPORATION (US) 1990-03-20 US disclosed