⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712393 | 0.79 | — | — | |
| SCHEMBL9712428 | 0.79 | — | — | |
| SCHEMBL10444149 | 0.76 | — | — | |
| SCHEMBL9712411 | 0.72 | — | — | |
| SCHEMBL9712407 | 0.71 | — | — | |
| SCHEMBL11973541 | 0.71 | — | — | |
| SCHEMBL9712348 | 0.69 | — | — | |
| SCHEMBL2353911 | 0.67 | — | — | |
| SCHEMBL9712370 | 0.66 | — | — | |
| SCHEMBL9707328 | 0.62 | ACHE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| US-4628110-A | Novel 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-12-09 | — | — | US | disclosed |
| EP-0092352-B1 | 9-SUBSTITUTED CARBACYCLINS | THE UPJOHN COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| EP-0086611-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-21 | — | — | EP | disclosed |
| US-4590297-A | Novel 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4588823-A | 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0086612-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4533749-A | 9-Substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| US-4525586-A | Composition and process | THE UPJOHN COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| US-4487961-A | ANTIULCER, ANTIASTHMA, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4032543-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-06-28 | — | — | US | disclosed |
| US-4029681-A | 13,14-Didehydro-PG analogs | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4028419-A | PROSTAGLANDINS | THE UPJOIN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4028350-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4020173-A | 4α,6-Dihydroxy-2β-carboxaldehyde-3α-tetrahydropyranacetic acid γ-lactone, 6-alkyl ethers | THE UPJOHN COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4018804-A | PROSTAGLANDINS AND DERIVATIVES | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |