Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015170 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1KCNJ1TSHRCYP1A2 | |
| SCHEMBL4168460 | 0.78 | TDP1 (0.45) | TDP1ALDH1A1KCNJ1TSHRCYP1A2 | |
| SCHEMBL8604197 | 0.78 | ALDH1A1 (0.38) | TDP1ALDH1A1KCNJ1TSHRERN1 | |
| SCHEMBL1708271 | 0.78 | ALDH1A1 (0.43) | TDP1ALDH1A1KCNJ1TSHRCYP1A2 | |
| SCHEMBL31303741 | 0.78 | ALDH1A1 (0.43) | TDP1ALDH1A1KCNJ1TSHRCYP1A2 | |
| SCHEMBL3842233 | 0.78 | TDP1 (0.45) | TDP1ALDH1A1ERN1MEN1KMT2A | |
| SCHEMBL10989431 | 0.77 | TDP1 (0.43) | TDP1ALDH1A1KCNJ1ERN1NSD2 | |
| SCHEMBL23835305 | 0.75 | ERN1 (0.46) | TDP1ALDH1A1ERN1POLBL3MBTL1 | |
| SCHEMBL30151958 | 0.75 | ERN1 (0.46) | TDP1ALDH1A1ERN1POLBL3MBTL1 | |
| SCHEMBL19948618 | 0.75 | ERN1 (0.39) | TDP1ALDH1A1KCNJ1TSHRERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |