SCHEMBL9712563

SCHEMBL9712563

Cc1cccc(C(=O)Cl)c1.ClCc1ccc2c(c1)OCO2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
MEN1 O00255 2/20 0.50
LMNA P02545 2/20 0.50
CTNNB1 P35222 1/20 0.50
WNT3A P56704 1/20 0.50
MAPK1 P28482 1/20 0.50
MMP13 P45452 1/20 0.50
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HPGD P15428 2/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP3A4 P08684 1/20 0.46
POLB P06746 2/20 0.46
ALDH1A1 P00352 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
ALDH2 P05091 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoyl Chloride SCHEMBL9712619 0.85 CTNNB1 (0.54) KMT2ANPC1RAB9AMEN1LMNA
SCHEMBL25202633 0.81 CTNNB1 (0.60) KMT2ANPC1RAB9AMEN1LMNA
Toluene SCHEMBL27970902 0.80 KMT2A (0.50) KMT2ANPC1RAB9AMEN1LMNA
SCHEMBL29642903 0.76 TAAR1 (0.60) MAPTCYP3A4ALDH1A1
SCHEMBL50478 0.76 TAAR1 (0.60) MAPTCYP3A4ALDH1A1
SCHEMBL15980026 0.75 CTNNB1 (0.84) KMT2ANPC1RAB9AMEN1CTNNB1
Methylene Chloride SCHEMBL29186228 0.74 TAAR1 (0.58) MAPTCYP3A4ALDH1A1
Methane SCHEMBL27598295 0.74 TAAR1 (0.58) MAPTCYP3A4ALDH1A1
SCHEMBL103438 0.74 PARP1 (0.63) KMT2ANPC1RAB9AMEN1SMN1; SMN2
SCHEMBL29365229 0.74 PARP1 (0.63) KMT2ANPC1RAB9AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed