SCHEMBL103438

SCHEMBL103438

Cc1cccc(C(=O)Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.63
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.55
KCNK3 O14649 3/20 0.53
KCNK9 Q9NPC2 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HPGD P15428 2/20 0.53
KCNH2 Q12809 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
POLB P06746 2/20 0.52
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
NPC1 O15118 1/20 0.49
TP53 P04637 1/20 0.49
RAB9A P51151 1/20 0.49
RXFP1 Q9HBX9 1/20 0.48
ACHE P22303 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365229 1.00 PARP1 (0.63) PARP1HDAC8HDAC6SMN1; SMN2KCNK3
Benzoyl Chloride SCHEMBL10954201 0.94 SMN1; SMN2 (0.59) PARP1HDAC8HDAC6SMN1; SMN2KCNK3
SCHEMBL11629322 0.89 PARP1 (0.56) PARP1HDAC8HDAC6SMN1; SMN2KCNK3
Benzoyl Chloride SCHEMBL8734541 0.87 SMN1; SMN2 (0.56) PARP1HDAC8HDAC6SMN1; SMN2KCNK3
SCHEMBL9712399 0.86 KCNK3 (0.55) PARP1HDAC8HDAC6SMN1; SMN2KCNK3
SCHEMBL7729073 0.84 KCNK3 (0.63) PARP1KCNK3KCNK9MEN1KMT2A
SCHEMBL2105158 0.83 KCNK3 (0.79) KCNK3KCNK9MEN1KMT2AKCNH2
Choline SCHEMBL11333452 0.83 PARP1 (0.46) PARP1HDAC8HDAC6SMN1; SMN2KCNK3
SCHEMBL27510 0.83 ALDH1A1 (0.59) PARP1HDAC8HDAC6TDP1ALDH1A1
SCHEMBL27537612 0.83 PARP1 (0.59) PARP1HDAC8HDAC6SMN1; SMN2KCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2142 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284203-B Tanshinone IIA C-1 position esterified derivative and preparation method and application thereof 郑州大学 2025-06-10 CN claimed
CN-119775127-A Continuous production process and production device of m-methylbenzoyl chloride 山东凯盛新材料股份有限公司 2025-04-08 CN claimed
CN-119306629-A Preparation method of m-cyanomethyl benzoate 甘肃汉隆化工有限公司 2025-01-14 CN claimed
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO claimed
CN-119098067-A Method for producing reverse osmosis membrane and reverse osmosis membrane produced thereby 沃顿科技股份有限公司 2024-12-10 CN claimed
CN-118914412-A Method for detecting midbody and isomer impurity thereof 北京海步医药科技有限公司 2024-11-08 CN claimed
CN-117468118-B Antibacterial PET composite fiber and preparation method thereof 北京清大际光科技发展有限公司 2024-10-29 CN claimed
CN-115448869-B Preparation method of intermediate for synthesizing spirotetramat 顺毅南通化工有限公司 2024-08-09 CN claimed
CN-117468118-A Antibacterial PET composite fiber and preparation method thereof 北京清大际光科技发展有限公司 2024-01-30 CN claimed
CN-116333672-B UV (ultraviolet) binder suitable for camera module and preparation method thereof 广东德聚技术股份有限公司 2023-11-17 CN claimed
US-20010018539-A1 Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs CHAN, KEITH 2001-08-30 US claimed
WO-2000061536-A2 SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS GLOBOASIA, L.L.C. (US) 2000-10-19 WO claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
EP-0158000-B1 REGIO AND OPTICAL ISOMERS OF IMIDAZOLINYL TOLUIC ACIDS, ESTERS AND SALTS, THEIR METHOD OF PREPARATION AND THEIR USE AS HERBICIDAL AGENTS AMERICAN CYANAMID COMPANY (US) 1991-06-19 EP claimed
EP-0158000-A1 Regio and optical isomers of imidazolinyl toluic acids, esters and salts, their method of preparation and their use as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1985-10-16 EP claimed
US-4414406-A MOLYBDENUM SULFIDE, SILICIDE, SELENIDE OR TELLURIDE STANDARD OIL COMPANY (INDIANA) (US) 1983-11-08 US claimed
US-4332740-A REACTION OF POTASSIUM SALT OF HYDROPEROXIDE WITH ACYL HALIDE IN NONPOLAR SOLVENT NIPPON OIL AND FATS CO., LTD. (JP) 1982-06-01 US claimed