SCHEMBL9712671

SCHEMBL9712671

CCCCCCCCC(CC)(CC)Cc1cc(N)[nH]n1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
CNR2 P34972 3/20 0.32
CNR1 P21554 2/20 0.32
GPR84 Q9NQS5 1/20 0.31
SOD3 P08294 2/20 0.31
SCN9A Q15858 2/20 0.31
SCN5A Q14524 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19973201 0.76 KCNH2 (0.44) LMNAMAPTSMN1; SMN2ALDH1A1HPGD
SCHEMBL1115983 0.64 TSHR (0.50)
SCHEMBL1116068 0.64 TSHR (0.50)
SCHEMBL31140203 0.64 TSHR (0.50)
SCHEMBL1115958 0.64 TSHR (0.50)
SCHEMBL1115960 0.64 TSHR (0.50)
SCHEMBL1116250 0.64 TSHR (0.50)
SCHEMBL8082452 0.64 TSHR (0.50)
SCHEMBL21925326 0.64 TSHR (0.50)
SCHEMBL1116260 0.64 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086184-A Herbicides DOWELANCO (US) 1992-02-04 US disclosed
US-4943634-A HERBICIDES ELI LILLY AND COMPANY (US) 1990-07-24 US disclosed
US-4801718-A HERBICIDES ELI LILLY AND COMPANY (US) 1989-01-31 US disclosed
US-4636243-A HERBICIDES ISOXAZOLES ELI LILLY AND COMPANY (US) 1987-01-13 US disclosed
US-4515625-A HERBICIDES ELI LILLY AND COMPANY (US) 1985-05-07 US disclosed
EP-0049071-B1 N-ARYLBENZAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1984-12-19 EP disclosed
US-4416683-A HERBICIDES ELI LILLY AND COMPANY (US) 1983-11-22 US disclosed
EP-0049071-A1 N-arylbenzamide derivatives ELI LILLY AND COMPANY (US) 1982-04-07 EP disclosed