Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713305 | 0.97 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9713161 | 0.94 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9713494 | 0.91 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9713343 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9713980 | 0.89 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9713124 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9712773 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9712622 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9712761 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10TP53ABL1 | |
| SCHEMBL9713050 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10TP53ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0049071-A1 | N-arylbenzamide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | disclosed |