Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144021 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRCES2NAAAEPHX1 | |
| SCHEMBL13034063 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRCES2NAAAEPHX1 | |
| SCHEMBL2254001 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRCES2NAAAEPHX1 | |
| SCHEMBL13817606 | 0.91 | TSHR (0.61) | ALDH1A1TSHRCES2NAAAMEN1 | |
| SCHEMBL6281199 | 0.91 | ALDH1A1 (0.78) | ALDH1A1TSHRCES2NAAAEPHX1 | |
| SCHEMBL22984496 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TSHRCES2NAAAMEN1 | |
| SCHEMBL10557713 | 0.89 | ALDH1A1 (0.68) | ALDH1A1TSHRCES2NAAAEPHX1 | |
| SCHEMBL10893909 | 0.89 | ALDH1A1 (0.82) | ALDH1A1TSHRCES2NAAAEPHX1 | |
| SCHEMBL2381459 | 0.89 | ALDH1A1 (0.82) | ALDH1A1TSHRCES2NAAAEPHX1 | |
| SCHEMBL6661477 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRCES2NAAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |