Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712775 | 0.93 | ACACB (0.50) | ACACBFFAR1FFAR4MCHR1PTGES2 | |
| SCHEMBL9713349 | 0.91 | ACACB (0.49) | ACACBFFAR1FFAR4MCHR1PTGES2 | |
| SCHEMBL9713010 | 0.91 | ACACB (0.49) | ACACBFFAR1FFAR4MCHR1TSHR | |
| SCHEMBL9713233 | 0.90 | ACACB (0.48) | ACACBFFAR1FFAR4MCHR1PTGES2 | |
| SCHEMBL9713085 | 0.90 | ACACB (0.48) | ACACBFFAR1FFAR4MCHR1PTGES2 | |
| SCHEMBL9713809 | 0.90 | ACACB (0.48) | ACACBFFAR1FFAR4MCHR1PTGES2 | |
| SCHEMBL9713435 | 0.89 | ACACB (0.49) | ACACBFFAR1FFAR4MCHR1PTGES2 | |
| SCHEMBL9495985 | 0.85 | ACACB (0.67) | ACACBFFAR1FFAR4MCHR1MAPT | |
| SCHEMBL8379711 | 0.85 | ACACB (0.52) | ACACBFFAR1TSHR | |
| SCHEMBL9712996 | 0.84 | ACACB (0.43) | ACACBFFAR1MCHR1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164114-A | LIQUID CRYSTAL | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1992-11-17 | — | — | US | disclosed |
| EP-0306521-B1 | ETHINE DERIVATIVES AS COMPOUNDS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |