Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713193 | 0.91 | ACACB (0.52) | ACACBMCHR1RXRAGRIN1GRIN2B | |
| SCHEMBL9713202 | 0.90 | ACACB (0.46) | ACACBMCHR1FFAR1FFAR4 | |
| SCHEMBL9712775 | 0.89 | ACACB (0.50) | ACACBMCHR1FFAR1FFAR4TSHR | |
| SCHEMBL9713349 | 0.87 | ACACB (0.49) | ACACBMCHR1FFAR1FFAR4L3MBTL1 | |
| SCHEMBL9713233 | 0.86 | ACACB (0.48) | ACACBMCHR1FFAR1FFAR4TSHR | |
| SCHEMBL9713809 | 0.86 | ACACB (0.48) | ACACBMCHR1FFAR1FFAR4TSHR | |
| SCHEMBL9713085 | 0.86 | ACACB (0.48) | ACACBMCHR1FFAR1FFAR4TSHR | |
| SCHEMBL9816286 | 0.86 | ACACB (0.52) | ACACBMCHR1L3MBTL1 | |
| SCHEMBL9496908 | 0.85 | ACACB (0.63) | ACACBMCHR1FFAR1FFAR4 | |
| SCHEMBL9713293 | 0.84 | ACACB (0.51) | ACACBMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164114-A | LIQUID CRYSTAL | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1992-11-17 | — | — | US | disclosed |
| EP-0306521-B1 | ETHINE DERIVATIVES AS COMPOUNDS OF LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |